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Usual Adult Dose for Infectious Diarrhea 500 mg orally every 12 hours for 5 to 7 days Use: When antibacterial therapy is indicated, for treatment of infectious diarrhea due to E coli (enterotoxigenic isolates), Campylobacter jejuni, Shigella boydii, S dysenteriae, S flexneri, or S sonnei Infectious Diseases Society of America (IDSA) recommendations: 500 mg orally twice a day Duration of therapy : -Immunocompetent patients: 3 days -Immunocompromised patients: 7 to 10 days Comments : -Recommended for Shigella species, E coli species (enterotoxigenic, enteropathogenic, enteroinvasive), Aeromonas, Plesiomonas -According to some experts, a single 1 g dose may be effective for non-dysentery shigellosis.
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Doctors choose an antibiotic based on its effectiveness against specific strains of bacteria, its strength against bacterial resistance, and its ease of use.
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It will be appreciated that when the unit dose is provided as a single unit, for instance a chewable tablet or a single dose sachet, such unit will comprise twice the above quantities.
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